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1

Plasticity of the epigenome during early-life stress

Burns, S. Barnett, Szyszkowicz, J. Kasia, Luheshi, Giamal N., Lutz, Pierre-Eric, Turecki, Gustavo

Journal:

Seminars in Cell & Developmental Biology

Year:

2017

Language:

english

File:

PDF, 2.06 MB

english, 2017

2

Interleukin-1α expression precedes IL-1β after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues

Nadia M Luheshi, Krisztina J Kovács, Gloria Lopez-Castejon, David Brough, Adam Denes

Journal:

Journal of Neuroinflammation

Year:

2011

Language:

english

File:

PDF, 573 KB

english, 2011

3

ANS Binding Reveals Common Features of Cytotoxic Amyloid Species

Bolognesi, Benedetta, Kumita, Janet R., Barros, Teresa P., Esbjorner, Elin K., Luheshi, Leila M., Crowther, Damian C., Wilson, Mark R., Dobson, Christopher M., Favrin, Giorgio, Yerbury, Justin J.

Journal:

ACS Chemical Biology

Year:

2010

Language:

english

File:

PDF, 2.30 MB

english, 2010

4

[Offshore Technology Conference Offshore Technology Conference - Houston, Texas, USA (2010-05-03)] Offshore Technology Conference - Offshore Petroleum Play Fairway Analysis and Geoscience Data Package Program

Van Belle, Olivier Stephan Eduard, Wilson, Hamish, Luheshi, Matt, MacMullin, Roderick Alexander, St-Amour, Wayne

Language:

english

File:

PDF, 5.10 MB

english

5

Prenatal infection leads to ASD-like behavior and altered synaptic pruning in the mouse offspring

Fernández de Cossío, Lourdes, Guzmán, Andrea, van der Veldt, Suzanne, Luheshi, Giamal N.

Journal:

Brain, Behavior, and Immunity

Year:

2016

Language:

english

File:

PDF, 1014 KB

english, 2016

6

Selective contribution of interleukin-6 and leptin to brain inflammatory signals induced by systemic LPS injection in mice

Christoph Rummel, Wataru Inoue, Christelle Sachot, Stephen Poole, Thomas Hübschle, Giamal N. Luheshi

Journal:

The Journal of Comparative Neurology

Year:

2008

Language:

english

File:

PDF, 2.42 MB

english, 2008

7

Spatiotemporal nuclear factor interleukin-6 expression in the rat brain during lipopolysaccharide-induced fever is linked to sustained hypothalamic inflammatory target gene induction

Jelena Damm, Giamal N. Luheshi, Rüdiger Gerstberger, Joachim Roth, Christoph Rummel

Journal:

The Journal of Comparative Neurology

Year:

2011

Language:

english

File:

PDF, 2.16 MB

english, 2011

8

Nuclear retention of IL-1α by necrotic cells: A mechanism to dampen sterile inflammation

Nadia M. Luheshi, Barry W. McColl, David Brough

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 2.72 MB

english, 2009

9

Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages

Nadia M. Luheshi, James A. Giles, Gloria Lopez-Castejon, David Brough

Journal:

European Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 431 KB

english, 2012

10

Chronic LPS exposure produces changes in intrinsic membrane properties and a sustained IL-β-dependent increase in GABAergic inhibition in hippocampal CA1 pyramidal neurons

Ian C. Hellstrom, Marc Danik, Giamal N. Luheshi, Sylvain Williams

Journal:

Year:

2005

Language:

english

File:

PDF, 191 KB

english, 2005

11

Acute brain cytokine responses after global birth hypoxia in the rat

Helen Ashdown, Silvia Joita, Giamal N. Luheshi, Patricia Boksa

Journal:

Journal of Neuroscience Research

Year:

2008

Language:

english

File:

PDF, 315 KB

english, 2008

12

Protein misfolding and disease: from the test tube to the organism

Leila M Luheshi, Damian C Crowther, Christopher M Dobson

Journal:

Current Opinion in Chemical Biology

Year:

2008

Language:

english

File:

PDF, 422 KB

english, 2008

13

1,3-dipolar cycloadditions of 2-Ethoxy- and 2-(ethylthio)-1-azetines with nitrile oxides, nitrile ylides and nitrilimines: An unexpected 1,2,4-triazole formation.

Karl Hemming, Abdul-Bassett N. Luheshi, Alan D. Redhouse, Robert K. Smalley, J.Robin Thompson, Peter D. Kennewell, R. Westwood

Journal:

Year:

1993

Language:

english

File:

PDF, 1.46 MB

english, 1993

14

Heterocycles by intramolecular aza-Wittig reactions of iminophosphoranes obtained from 2-azidobenzoyl- and 2-azidobenzylidene derivatives

A.-B.N. Luheshi, S.M. Salem, R.K. Smalley, P.D. Kennewell, R. Westwood

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 51 KB

english, 1991

15

1,3-Dipolar cycloadditions of 2-ethoxy- and 2-(ethylthio)-1-azetines with nitrilimines

Abdul-Basset N. Luheshi, Robert K. Smalley, P.D. Kennewell, R. Westwood

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 198 KB

english, 1990

16

1,3-Dipolar cycloadditions of 2-ethoxy- and 2-(ethylthio)-1-azetines with nitrile oxides and nitrile ylides

Abdul-Basset N. Luheshi, Robert K. Smalley, Peter D. Kennewell, Robert Westwood

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 194 KB

english, 1990

17

Heterocycles by intramolecular aza-Wittig reactions of iminophosphoranes obtained from 2-azidobenzoyl- and 2-azidobenzylidene derivatives

Abdul-Bassett N. Luheshi, Salem M. Salem, Robert K. Smalley, Peter D. Kennewell, Robert Westwood

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 196 KB

english, 1990

18

The vagus nerve mediates behavioural depression, but not fever, in response to peripheral immune signals; a functional anatomical analysis

Jan Pieter Konsman, Giamal N. Luheshi, Rose-Marie Bluthé, Robert Dantzer

Journal:

European Journal of Neuroscience

Year:

2000

Language:

english

File:

PDF, 880 KB

english, 2000

19

Expression of interleukin-1 receptors and their role in interleukin-1 actions in murine microglial cells

Emmanuel Pinteaux, Lisa C. Parker, Nancy J. Rothwell, Giamal N. Luheshi

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 286 KB

english, 2002

20

Interleukin-18 induces expression and release of cytokines from murine glial cells: interactions with interleukin-1β

Rachel D. Wheeler, David Brough, Rosalind A. Le Feuvre, Kiyoshi Takeda, Yoichiro Iwakura, Giamal N. Luheshi, Nancy J. Rothwell

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 291 KB

english, 2003

21

Fever and production of cytokines in response to repeated injections of muramyl dipeptide in guinea-pigs

Joachim Roth, Stephen J. Hopkins, Margaret E. Hoadley, Anke Tripp, Tunai Aslan, Birgit Störr, Giamal N. Luheshi, E. Zeisberger

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1997

Language:

english

File:

PDF, 718 KB

english, 1997

22

Estimation of formation temperature from borehole measurements

Journal:

Geophysical Journal International

Year:

1983

Language:

english

File:

PDF, 1.48 MB

english, 1983

23

The Role of the Vagus Nerve in Mediating the Long-Term Anorectic Effects of Leptin

C. Sachot, C. Rummel, A. F. Bristow, G. N. Luheshi

Journal:

Journal of Neuroendocrinology

Year:

2007

Language:

english

File:

PDF, 955 KB

english, 2007

24

Leptin induces cyclooxygenase-2 via an interaction with interleukin-1β in the rat brain

Wataru Inoue, Stephan Poole, Adrian F. Bristow, Giamal N. Luheshi

Journal:

European Journal of Neuroscience

Year:

2006

Language:

english

File:

PDF, 1001 KB

english, 2006

25

Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide

J. P. Konsman, J. Veeneman, C. Combe, S. Poole, G. N. Luheshi, R. Dantzer

Journal:

European Journal of Neuroscience

Year:

2008

Language:

english

File:

PDF, 617 KB

english, 2008

26

Brain sites of action of endogenous interleukin-1 in the febrile response to localized inflammation in the rat

T. Cartmell, G. N. Luheshi, N. J. Rothwell

Journal:

The Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 465 KB

english, 1999

27

Circulating interleukin-6 mediates the febrile response to localised inflammation in rats

T. Cartmell, S. Poole, A. V. Turnbull, N. J. Rothwell, G. N. Luheshi

Journal:

The Journal of Physiology

Year:

2000

Language:

english

File:

PDF, 280 KB

english, 2000

28

Role of endogenous interleukin-1 receptor antagonist in regulating fever induced by localised inflammation in the rat

T. Cartmell, G. N. Luheshi, S. J. Hopkins, N. J. Rothwell, S. Poole

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 344 KB

english, 2001

29

Leptin induces interleukin-1β release from rat microglial cells through a caspase 1 independent mechanism

Emmanuel Pinteaux, Wataru Inoue, Lorraine Schmidt, Francisco Molina-Holgado, Nancy J. Rothwell, Giamal N. Luheshi

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 639 KB

english, 2007

30

Dual functionality of interleukin-1 family cytokines: implications for anti-interleukin-1 therapy

NM Luheshi, NJ Rothwell, D Brough

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 304 KB

english, 2009

31

The Dynamics and Mechanisms of Interleukin-1α and β Nuclear Import

Nadia M. Luheshi, Nancy J. Rothwell, David Brough

Journal:

Year:

2009

Language:

english

File:

PDF, 935 KB

english, 2009

32

Cytokines and Fever: Mechanisms and Sites of Action

GIAMAL N. LUHESHI

Journal:

Annals of the New York Academy of Sciences

Year:

1998

File:

PDF, 578 KB

1998

33

10.1038/353

Luheshi, Giamal, Gardner, Jason, Rothwell, Nancy

Journal:

Nature Neuroscience

Year:

1998

Language:

english

File:

PDF, 45 KB

english, 1998

34

Leptin regulates leukocyte recruitment into the brain following systemic LPS-induced inflammation

Rummel, C, Inoue, W, Poole, S, Luheshi, G N

Journal:

Molecular Psychiatry

Year:

2009

Language:

english

File:

PDF, 798 KB

english, 2009

35

Brain TNF: Damage limitation or damaged reputation?

Rothwell, Nancy J., Luheshi, Giamal N.

Journal:

Nature Medicine

Year:

1996

File:

PDF, 260 KB

1996

36

Sites of action of IL-1 in the development of fever and cytokine responses to tissue inflammation in the rat

Andrew J. Miller, Stephen J. Hopkins, Giamal N. Luheshi

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 315 KB

english, 1997

37

IL-1β signalling in glial cells in wildtype and IL-1RI deficient mice

Lisa C Parker, Giamal N Luheshi, Nancy J Rothwell, Emmanuel Pinteaux

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 286 KB

english, 2002

38

Cloning of rat brain interleukin-18 cDNA

Culhane, A C, Hall, M D, Rothwell, N J, Luheshi, G N

Journal:

Molecular Psychiatry

Year:

1998

Language:

english

File:

PDF, 119 KB

english, 1998

39

The role of cytokines in mediating effects of prenatal infection on the fetus: implications for schizophrenia

Ashdown, H, Dumont, Y, Ng, M, Poole, S, Boksa, P, Luheshi, G N

Journal:

Molecular Psychiatry

Year:

2005

Language:

english

File:

PDF, 173 KB

english, 2005

40

No Role for Interleukin-18 in Acute Murine Stroke-Induced Brain Injury

Wheeler, Rachel D., Boutin, Herve, Touzani, Omar, Luheshi, Giamal N., Takeda, Kiyoshi, Rothwell, Nancy J.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2003

Language:

english

File:

PDF, 334 KB

english, 2003

41

Circulating leptin mediates lipopolysaccharide-induced anorexia and fever in rats

Christelle Sachot, Stephen Poole, Giamal N. Luheshi

Journal:

The Journal of Physiology

Year:

2004

Language:

english

File:

PDF, 261 KB

english, 2004

42

Attenuated fever in rats during late pregnancy is linked to suppressed interleukin-6 production after localized inflammation with turpentine

Argel Aguilar-Valles, Stephen Poole, Yogesh Mistry, Sylvain Williams, Giamal N. Luheshi

Journal:

The Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 588 KB

english, 2007

43

Cytokines and their receptors in the central nervous system: Physiology, pharmacology, and pathology

Nancy J. Rothwell, Giamal Luheshi, Sylvie Toulmond

Journal:

Pharmacology & Therapeutics

Year:

1996

Language:

english

File:

PDF, 1.62 MB

english, 1996

44

On the use of animal modeling to study maternal infection during pregnancy and prenatal cytokine exposure as risk factors for schizophrenia

Patricia Boksa, Giamal N. Luheshi

Journal:

Clinical Neuroscience Research

Year:

2003

Language:

english

File:

PDF, 152 KB

english, 2003

45

Bridging the gap: From protein misfolding to protein misfolding diseases

Leila M. Luheshi, Christopher M. Dobson

Journal:

Year:

2009

Language:

english

File:

PDF, 426 KB

english, 2009

46

Altered expression of lipid metabolism and immune response genes in the frontal cortex of suicide completers

Aleksandra Lalovic, Tim Klempan, Adolfo Sequeira, Giamal Luheshi, Gustavo Turecki

Journal:

Journal of Affective Disorders

Year:

2010

Language:

english

File:

PDF, 409 KB

english, 2010

47

Identification of a truncated IL-18Rβ mRNA: a putative regulator of IL-18 expressed in rat brain

Ralph Andre, Rachel D. Wheeler, Peter D. Collins, Giamal N. Luheshi, Stuart Pickering-Brown, Ian Kimber, Nancy J. Rothwell, Emmanuel Pinteaux

Journal:

Journal of Neuroimmunology

Year:

2003

Language:

english

File:

PDF, 358 KB

english, 2003

48

Maternal exposure to bacterial endotoxin during pregnancy enhances amphetamine-induced locomotion and startle responses in adult rat offspring

Marie-Ève Fortier, Ridha Joober, Giamal N Luheshi, Patricia Boksa

Journal:

Journal of Psychiatric Research

Year:

2004

Language:

english

File:

PDF, 274 KB

english, 2004

49

Alterations in cognitive function and behavioral response to amphetamine induced by prenatal inflammation are dependent on the stage of pregnancy

Argel Aguilar-Valles, Giamal N. Luheshi

Journal:

Psychoneuroendocrinology

Year:

2011

Language:

english

File:

PDF, 620 KB

english, 2011

50

Leptin and interleukin-6 alter the function of mesolimbic dopamine neurons in a rodent model of prenatal inflammation

Argel Aguilar-Valles, Suna Jung, Stephen Poole, Cecilia Flores, Giamal N. Luheshi

Journal:

Psychoneuroendocrinology

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012